Is your current treatment enough?

Carcinoid Syndrome Diarrhea (CSD) can upend your life

  • 83% of patients living with Carcinoid Syndrome (CS) report it is a daily challenge1
  • 84% of patients say CSD causes disruptions in everyday life1
  • 88% of patients agree that symptoms make life more stressful1

CSD impacts every aspect of your life

Physical2,3

  • Dehydration
  • Pain
  • Fatigue
  • Weight loss

Psychological3

  • Depression
  • Anxiety
  • Unhappiness with social life

Quality of life

  • People with greater-than-average daily bowel movements (BMs) had worse scores on a health-related quality of life (HRQL) survey3

Somatostatin analog (SSA) treatment alone may not be enough

  • Despite SSA treatment, many patients stop responding over time4
  • Escalating SSA dose or increasing frequency may not always be appropriate4
  • Taking over-the-counter medications or supplements may provide some temporary relief, but they won’t specifically target the cause of CSD4

Improvement is possible with XERMELO

If SSA injections aren’t giving you the control you need, you’re not alone. Over half of patients say their current treatments don’t do enough to control their CSD.1 Even if you know what triggers it, what foods to avoid in your diet, and how to stay on track with SSA treatment, you may still have diarrhea due to an overproduction of serotonin.4

If CSD has forced you to redefine everyday life, this doesn’t have to be your normal. See how adding XERMELO can help.

Ask your doctor if XERMELO could be right for you

Download this discussion guide to get the conversation started.

Download discussion guide

How XERMELO helps

See the study results in CSD

See the results

What is CSD?

Find out the causes, symptoms, and role of serotonin

Learn about CSD

Questions about treatment?

Contact a nurse who specializes in CSD

Get dedicated support

References

  1. Data on File. TerSera Therapeutics LLC. Deerfield, IL.
  2. Anthony LB. Practical guide to supportive care of patients with functional neuroendocrine tumors. Semin Oncol. 2013;40(1):45-55.
  3. Beaumont JL, Cella D, Phan AT, Choi S, Liu Z, Yao JC. Comparison of health-related quality of life in patients with neuroendocrine tumors with quality of life in the general US population. Pancreas. 2012;41(3):461-466.
  4. Naraev BG, Halland M, Halperin DM, Purvis AJ, O’Dorisio TM, Halfdanarson TR. Management of diarrhea in patients with carcinoid syndrome. Pancreas. 2019;48(8):961-972

IMPORTANT SAFETY INFORMATION

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • The most common side effects of XERMELO include nausea, headache, increase in liver enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, fever, abdominal pain, and constipation.
  • Talk to your doctor about all medications you are taking as some may interact with XERMELO.
  • XERMELO is not recommended if you have moderate or severe liver impairment.

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for Carcinoid Syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

You are encouraged to report negative side effects of prescription drugs to the FDA. To report suspected adverse reactions, contact the FDA at 1-800-FDA-1088 or www.FDA.gov/medwatch. You may also contact TerSera Therapeutics at 1-844-334-4035 or medicalinformation@tersera.com.

Please see Full Prescribing Information.

 

IMPORTANT SAFETY INFORMATION

  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • Do not take XERMELO if you have a history of hypersensitivity to telotristat or any of the ingredients in XERMELO.
  • XERMELO may cause constipation which can be serious. You should stop taking XERMELO if severe constipation or severe, persistent, or worsening abdominal pain develops. Talk to your doctor if you have these symptoms.
  • The most common side effects of XERMELO include nausea, headache, increase in liver enzymes, depression, flatulence, decreased appetite, swelling of your hands and feet, fever, abdominal pain, and constipation.
  • Talk to your doctor about all medications you are taking as some may interact with XERMELO.
  • XERMELO is not recommended if you have moderate or severe liver impairment.

Indication

XERMELO is a prescription pill, used along with somatostatin analog (SSA) therapy, for Carcinoid Syndrome diarrhea in adults who are not adequately controlled by SSA therapy.

You are encouraged to report negative side effects of prescription drugs to the FDA. To report suspected adverse reactions, contact the FDA at 1-800-FDA-1088 or www.FDA.gov/medwatch. You may also contact TerSera Therapeutics at 1-844-334-4035 or medicalinformation@tersera.com.

Please see Full Prescribing Information.

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